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Bone Texture Fractal Dimension Analysis of Ultrasound-Treated Bone around Implant Site: A Double-Blind Clinical Trial

机译:植入部位周围经超声处理的骨的骨纹理分形维分析:一项双盲临床试验

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Objectives. To evaluate the efficacy of bone texture fractal dimension (FD) analysis method in predicting implant stability from intraoral periapical radiographs using two implant protocols. Materials and Methods. A double-blind clinical trial was conducted on 22 subjects who needed dental implants. The participants were randomized into two groups, the control group with standard implant protocol treatment and the intervention group with added low-intensity power ultrasound treatment (LIPUS) besides the standard implant protocol. The FD values of bone density were carried out on the mesial and distal sides of the implant on digital intraoral radiographs using the box-counting method. Both resonance frequency (RF) and fractal dimension (FD) were assessed in three time intervals after surgery and before and after loading. Results. FD on both the mesial and distal sides serve as very good-to-excellent tests with high validity (ROC area exceeding 0.8) in predicting high implant stability (ISQ ≥ 70). The mesial side measurements were consistently better than the distal side among the intervention groups. The optimum cutoff value for the FD-mesial side that predicts a highly stable implant (ISQ ≥ 70) is ≥1.505. At this optimum cutoff value, the mesial side FD is associated with a perfect sensitivity (100%) and fairly high specificity (86.5%). Conclusion. The FD analysis could be recommended as an adjunctive quantitative method in prediction of the implant stability with very high sensitivity and specificity. This trial is registered with ISRCTN72648040.
机译:目标。若要评估骨质构分形维数(FD)分析方法在使用两种植入方案从口腔根尖周X光片预测植入物稳定性中的功效。材料和方法。对需要牙种植体的22位受试者进行了一项双盲临床试验。参与者被随机分为两组,除标准植入方案外,对照组采用标准植入方案治疗,干预组采用低强度功率超声治疗(LIPUS)。骨密度的FD值是使用盒计数法在数字口内X光片上在植入物的中,远侧进行的。在手术后以及加载前后三个时间间隔内评估共振频率(RF)和分形维数(FD)。结果。在预测植入物的高稳定性(ISQ≥70)时,内侧和远端的FD都是非常好的测试,具有很高的有效性(ROC面积超过0.8)。在干预组中,内侧测量始终优于远端测量。可以预测植入物高度稳定(ISQ≥≥70)的FD切入侧的最佳截止值为≥1.505。在此最佳截止值下,近中侧FD具有理想的灵敏度(100%)和相当高的特异性(86.5%)。结论。 FD分析可被推荐作为辅助定量方法,以非常高的灵敏度和特异性预测植入物的稳定性。该试用版已在ISRCTN72648040中注册。

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