Coexistence of multiple metastatic lesions showing various grades of differentiation in a single patient with neuroendocrine tumor of lung as primary: A combined modality approach of 68Ga-DOTANOC positron emission tomography/computed tomography and 18F-fluorodeoxyglucose positron emission tomography/computed tomography imaging




Neuroendocrine tumors (NETs) of gastrointestinal (GI) tract and lungs are a rare variety of tumors but given their indolent nature are quite prevalent. These tumors are mostly malignant in nature and are often diagnosed in advanced stages. GI tracts are the most common sites of NETs followed by lungs, thymus, and other less common sites being ovaries, testis, and hepatobiliary system. Nuclear medicine imaging modalities include sup68/supGa-DOTANOC positron emission tomography/computed tomography (PET/CT) which is sensitive for low-grade NETs and sup18/supF-fluorodeoxyglucose (FDG) PET/CT which is more valuable for high-grade NETs. However, intermediate-grade NETs are equally sensitive to both sup68/supGa-DOTANOC PET/CT and 18F-FDG PET/CT.
机译:胃肠道(GI)和肺部的神经内分泌肿瘤(NET)是一种罕见的肿瘤,但鉴于其惰性,这种疾病非常普遍。这些肿瘤本质上大多数是恶性的,并且通常被诊断为晚期。胃肠道是NET的最常见部位,其次是肺,胸腺,其他较不常见的部位是卵巢,睾丸和肝胆系统。核医学成像模式包括对低级NETs敏感的 68 Ga-DOTANOC正电子发射断层扫描/计算机断层扫描(PET / CT)和 18 F-氟脱氧葡萄糖(FDG) PET / CT对于高级NET更有价值。但是,中级NET对 68 Ga-DOTANOC PET / CT和18F-FDG PET / CT都同样敏感。



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