THE INCIDENCE OF MYCOBACTERIUM TUBERCULOSIS INFECTIONS AND RESISTENCE TO ANTITUBERCULOSIS DRUGS IN GIURGIU POPULATION

摘要

Tuberculosis due to Mycobacterium tuberculosis is an important health problem all over the world. Correct and early diagnosis of infection is a major condition for efficient treatment. Different localizations of mycobacterial infection are occurred but the most important is the pulmonary tuberculosis. Pulmonary tuberculosis can be diagnosed by medical history and symptoms, laboratory and radiographic tests Laboratory diagnosis of mycobacterial infections required microscopic examinations of sputum for acid – fast bacilli and a culture from sputum sample. Other techniques have provided a rapid and modern diagnosis but required high cost and special settings. In 2012, 975 subjects are investigated for mycobacterial infection in Izvoru (Giurgiu) Pneumophtysiology Hospital, but just 34.8% from all were confirmed with M. tuberculosis infection. The micobacterial infections were related to other diseases and formulated in order to gender and age of patients. For these patients the antibiogram was performed. All bacterial strains from patients with initial infection were sensitive to antituberculosis drugs (Hydrazide and Rifampicin). Some bacterial strains from older infections were resistant to these drugs