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Oxidation Induced Changes in Lipid Mobility in Lipoproteins Followed by Steady State Fluorescence Anisotropy

机译:氧化诱导脂蛋白脂质运动的变化,随后是稳态荧光各向异性

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摘要

The oxidation induced changes in the lipid layer of the lipoprotein particles of LDL and HDLs have been followed by measuring the steady-state polarization anisotropy of the fluorescence probe TMA-DPH incorporated in the lipid layer. The mobility restriction Gradually increases with oxidation in LDL and HDL_2 indicating The oxidation-induced structuring of lipids, while the effect of oxi- Dation in HDL_3 is negligible.
机译:氧化诱导的LDL和HDL脂蛋白颗粒的脂层变化是通过测量掺入脂层的荧光探针TMA-DPH的稳态极化各向异性来实现的。随着LDL和HDL_2中的氧化,迁移率限制逐渐增加,表明氧化诱导的脂质结构化,而HDL_3中的氧化作用可忽略不计。

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