Metal binding calixarenes with potential biomimetic and biomedical applications

摘要

This article exploits the special geometry of calixarene derivatives and the resulting metal binding properties with a focus on biomedical applications. The use of calixarenes as mimics of ion channels through artificial cell membranes, as mimics of metalloenzymes, and in the promising emerging field of calixarene based agents for medical imaging and radiotherapy is summarized.