Quantitative GC-MS Method for the Determination of Aniline, Chlorocanili- Ne and Toluidine Released from Inks Of Ballpoint and Fiber-tip Pens

摘要

A GC-MS method concerning the identification and quantitative determination of free aniline, chloroanilines and toluidines in inks of ballpoint and fiber-tip pens is presented. Fluctuations of sensitivity of the mass detector are compensated by using deuterated aniline as an internal standard. O-, m- and p-isomers having different carcinogenic potentials can be discriminated by specific masses of their perfluoroac- yl derivatives. Results obtained for aniline and toluidine in ink samples show good agreement with our HPLC-method.