Trigger happy

摘要

The new SteriShield Delivery System safeguards the continued sterility of the contents of trigger spray bottles by eliminating the risks associated with 'suck-back'. In a conventional trigger spray suck-back allows potentially contaminated air into the bottle, which can in turn contaminate the liquid inside. Since its introduction, the system has been widely used to protect successfully the integrity of sterile alcohols, biocides and neutral detergents in trigger spray presentations for pharmaceutical applications. A validation study was designed to explore the potential risk of contamination being brought into a system via the only possible point of entry, the trigger head. The study compared the number of 0.5pm and 5pm particles drawn into various trigger systems, including the SteriShield Delivery System trigger, during use to present a quantified assessment of the risks from suck-back. The new trigger system has two main component parts: the bottle with a co-extruded integral Surlyn bag, and the trigger head. The liquid is held inside the bag and the function of the bottle is simply to enclose and protect the bag in use.