Insulin sensitivity after pancreaticoduodenal transplantation with systemic and portal venous drainage in inbred rats

摘要

Conclusion These data imply that portal venous drainage of the transplantation pancreas is an important factor in the determined of peripheral insulin sensitivity. Objective To assess the metabolic consequences of pancreatic transplantation with portal venous Drainage and systemic venous drainage in induced inbred rats with streptozocin. Methods Pancreaticoduodenal transplantation was performed on 8 rats with the donor portal veins Anastomosed to the recipient mesenteric vein and on 10 rats with the donor portal veins Anastomosed to the recipient cava inferior vein.