Phase behavior of mixtures containing antibiotics. Chloramphenicol partitioning

摘要

Phase equilibrium behavior of antibiotics is important in drug design and for optimization of the recovery processes manufacturing. Antibiotics are high-cost fine chemicals, mostly manufactured by fermentation using inexpensive substrates. The major cost of manufacturing is involved in the separation processes. The aqueous/organic partitioning behavior of a clinically important antibiotic, chloramphenicol, is measured.