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A preliminary assessment of the potential environmental and human health impact of unsymmetrical dimethylhydrazine as a result of space activities

机译:对不对称二甲基肼由于空间活动造成的潜在环境和人类健康影响的初步评估

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A preliminary assessment of the potential environmental and human health impact of UDMH as a result of space activities has been carried out applying a theoretical approach in comparison with selected experimental data. The theoretical framework includes QSAR, ADME and PASS modelling as well as studies on the possible atmospheric dispersion of UDMH as calculated applying the OML-Multi model. The possible impact on the environment and the human health has been elucidated and it has been concluded that UDMH especially inside the fall region of burned-out rocket stages constitute a significant threat to both environmental and human health, the latter as a results of the carcinogenic, mutagenic, convulsant, teratogenic and embryotoxic characteristics of UDMH in addition to the general toxic characteristics of the compound.
机译:已通过理论方法与选定的实验数据进行了对UDMH太空活动对环境和人类健康的潜在影响的初步评估。理论框架包括QSAR,ADME和PASS建模,以及使用OML-Multi模型计算得出的UDMH可能的大气扩散的研究。已经阐明了对环境和人类健康的可能影响,并且得出的结论是,UDMH,尤其是在烧尽的火箭级坠落区域内部,对环境和人类健康均构成重大威胁,后者是致癌性的结果除了该化合物的一般毒性特征外,还具有UDMH的致突变,惊厥,致畸和胚胎毒性特征。

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