Synthetic Carbohydrate Vaccines Based on Tumour-Associated Antigens

摘要

The confluence of chemistry and immunology has cultivated a new approach to vaccine development, i.e. a totally synthetic vaccine. One of the merits of synthetic vaccines lies in their structural simplicity, allowing ready accessibility, characterization, and manipulation. It is, therefore, possible to study the structure-activity relationship in order to design more effective vaccines. As the combined efforts of chemists and immunolo-gists continue, success in creating totally synthetic vaccines might become a reality in the not too distant future.