Designing New Lattice Inclusion Hosts

摘要

The discovery of new lattice inclusion hosts traditionally has been an exciting but entirely serendipitous branch of chemistry. Although crystal lattice arrangements of organic molecules still cannot be predicted by computation, our rapidly-developing understanding of molecular packing, intermolecular attractions, and crystal engineering techniques, is rapidly changing this situation. This article surveys major synthetic approaches currently being employed in the design of new lattice inclusion compounds, and attempts to describe how and why these compounds operate as host-guest systems in terms of their supramolecular chemistry.