Molecular modelling of electron transfer systems by noncovalently linked porphyrin-acceptor pairing

摘要

In the respiratory system, electron carriers such as ubiquinone and cytochrome c play an important role in the electron transfer (ET) reaction between oxidoreductases embedded in the mitochondrial membrane, This review focuses on a strategy for constructing porphyrin-electron acceptor pairs via specific interactions and the evaluation of ET in these systems, Particularly, the molecular recognition of ubiquinone analogues by porphyrin host molecules and the mimicking of protein-protein complexation using myoglobin reconstituted with a synthetic porphyrin are reviewed, and the characteristics of the photoinduced ET within noncovalently linked complexes are discussed.