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Identification and expression of epidermal growth factor gene in mouse testis

机译:小鼠睾丸中表皮生长因子基因的鉴定与表达

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Epidermal growth factor (EGF) is produced primarily by Leydig cells of human testis. Expression of the EGF gene was assessed in mouse testis during the course of sexual maturation by the application of the RT-PCR method and the use of specific oligonucleotide primers. Testis EGF mRNA content increased with the developmental age of the mice, i.e., day 15 < day 30 < day 45 postnatal. The expression of the EGF gene appears to correlate with maturation of the testis and proliferation of Leydig cells.
机译:表皮生长因子(EGF)主要由人睾丸的Leydig细胞产生。通过使用RT-PCR方法和使用特定的寡核苷酸引物,在性成熟过程中评估了小鼠睾丸中EGF基因的表达。睾丸EGF mRNA含量随小鼠的发育年龄而增加,即出生后15天<30天<45天。 EGF基因的表达似乎与睾丸的成熟和Leydig细胞的增殖有关。

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