Evidence for a mouse brain-specific variant ofα-tubulin

摘要

While studying the neural precursor cell intermediate filament protein known as nestin in the developing mouse brain, we observed a strong cross-reaction of our nestin an- tibody with a 50 kDa protein that appeared on embryonic day 10 and continued to accumulated until postnatal day 1. Here we report evidence that this protein is a brain-specific Variant from ofα-tubulin and discuss its implications.