The convergent point of the endocytic and autophagic pathways in leydig cells

摘要

Endocytic tracers and marker enzyme of lysosomes were used in the present study to analyze the processes of autophoagocysis and endocytosis, and the convergent point of these two pathways in Leydig cells. The endocytic and autophagic compartments can be easily identified in Leydig cells, which makes easier to define the stages of two Pathways than was possible before. The evidences indi- Cated that the late endosomes(dense MVBs)deliver their Endocytosed gold tracers together with lysosomal enzymes To the early autophagosomes and they are the convergent Point of the two pathways.