Short comminication Involvement of gene expression in apoptosis of vascu- Lar endothelial cells induced by rattlesnake venom

摘要

Formation of apoptosis bodies is a typical character of opoptotic cell death, but how the processes are controlled is not known. In this study, we compared two apoptosis inducing systems in vascular endothelial cells(VEC). We found that the formation of apoptotic bodies during apop- tosis induced by rattlesnake venom, which is an unique and specific apoptosis inducer to vascular endothelial cells, was much faster than that induced by deprivation of survival factors(aFGF and serum).