The developmental fate of green fluorescent mouse em- bryonic germ cells in chimeric embryos

摘要

Primordial germ cells(PGCs), as precursors of mam- malian germ lineage, have been gaining more attention as a new resource of pluripotent stem cells, which bring a great possibility to study developmental events of germ cell in vitro and at animal level. EG4 cells derived from 10.5 days post coitum(dpc)PGCs of 129/svJ strain mouse were established and maintained in an undifferentiated state.