Short communicaton: Ni~2+ treatment causes cement gland formation in ecto- Derm explants of xenopus laevis embryo

摘要

We found T-type calcium channel blocker Ni~2+ can ef- ficiently induce the formation of cement gland in Xenopus laevis animal cap explants. Another T-type specific cal- cium channel blocker Amiloride can also induce the forma- tion of cement gland, while L-type specific calcium channel blocker Nifedipine has no inductive effect. These results may offer us an new approach to study the differentiation of cement gland through the change of intracellular calcium concentration.