CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin

Sheng-ran Liang; Guang-rui Hu; Li-juan Fang; Su-jing Huang; Jin-song Li; Ming-yi Zhao; Min-jie Meng

首页> 外文期刊>Cancer Cell International >CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin

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CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin

机译：CpG寡脱氧核苷酸通过下调抗凋亡因子survivin和livin增强HepG2人肝癌细胞中5-氟尿嘧啶的化学敏感性

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Background Recent studies indicated that a synthetic oligonucleotide containing un-methylated CpG oligodeoxynucleotides (CpG-ODN) has a potential function for cancer therapy. In this study, we evaluated the chemosensitizing effects of CpG-ODN in 5-fluorouracil (5-FU)-treated HepG2 human hepatoma cells.

机译：背景技术最近的研究表明，含有未甲基化的CpG寡脱氧核苷酸（CpG-ODN）的合成寡核苷酸具有用于癌症治疗的潜在功能。在这项研究中，我们评估了CpG-ODN在5-氟尿嘧啶（5-FU）处理的HepG2人肝癌细胞中的化学增敏作用。

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《Cancer Cell International 》 |2013年第1期| 1-10| 共10页
作者
Sheng-ran Liang; Guang-rui Hu; Li-juan Fang; Su-jing Huang; Jin-song Li; Ming-yi Zhao; Min-jie Meng;
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CpG-ODN Human hepatoma cells Chemosensitizer Apoptosis Cell cycle arrest Livin Survivin;

机译：CpG-ODN人肝癌细胞化学增敏剂凋亡细胞周期停滞Livin Survivin;

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1. CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin [J] . Sheng-ran Liang, Guang-rui Hu, Li-juan Fang, Cancer Cell International . 2013 ,第1期

机译：CpG寡脱氧核苷酸通过下调抗凋亡因子survivin和livin增强人类HepG2肝癌细胞中5-氟尿嘧啶的化学敏感性
2. CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin [J] . Sheng-ran Liang, Guang-rui Hu, Li-juan Fang, Cancer Cell International . 2013 ,第1期

机译：CpG寡脱氧核苷酸通过下调抗凋亡因子survivin和livin增强人类HepG2肝癌细胞中5-氟尿嘧啶的化学敏感性
3. CpG Oligodeoxynucleotide Promotes Apoptosis of Human Bladder Cancer T24 Cells Via Inhibition of the Antiapoptotic Factors [J] . Yang Luo, Yuhang Dong, Shengran Liang, Technology in cancer research & treatment. . 2019 ,第6期

机译：CpG寡脱氧核苷酸通过抑制抗污染因子促进人膀胱癌T24细胞的凋亡
4. Inhibiting survivin expression increases the radiosensitivity of human hepatoma HepG2 cells to high-LET carbon ions [C] . X.D. Jin, Q. Li, P. Li, World congress on medical physics and biomedical engineering . 2009

机译：抑制Survivin表达增加了人肝癌HepG2细胞的放射敏感性至高碳离子
5. Albumin-derived nanoparticles: A flexible biointerface for enhanced adhesion, spatial guidance and growth factor stimulation of human mesenchymal stem cells. [D] . Xu, Jing. 2010

机译：白蛋白衍生的纳米颗粒：灵活的生物界面，可增强人间充质干细胞的粘附力，空间引导和生长因子刺激。
6. CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin [O] . Sheng-ran Liang, Guang-rui Hu, Li-juan Fang, 2013

机译：CpG寡脱氧核苷酸通过下调抗凋亡因子survivin和livin增强HepG2人肝癌细胞中5-氟尿嘧啶的化学敏感性
7. CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin [O] . 2013

机译：CpG寡脱氧核苷酸通过下调抗凋亡因子survivin和livin增强HepG2人肝癌细胞中5-氟尿嘧啶的化学敏感性

CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin

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