Cable-Analysis of a Motor-nerve terminal Branch in a Volume Conductor

摘要

An equivalent electrical circuit is given for a branch of an amphibian motor-nerve terminal in a volume conductor. The circuit allows for longitudinal current flow inside the axon as well as between the axon and its Schwann cell sheath, and also for the radial leakage of current through the Schwann cell sheath. Analytical and numerical solutions are found for the spatial and time dependence of the membrane potential resulting from for the spatial and time dependence of the membrane potential resulting form the injection of depolarizing current pulses by external electrodes at one or two separate locations on the terminal. These solutions show distance away.