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Wrong biochemistry results

机译:错误的生化结果

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The success of analytical methods in clinical chemistry has led to a sense of security in the value of laboratory results. This is largely justified, as evidenced by the quality of laboratory performance assessed by external assurance schemes. Nevertheless, it is not widely recognised among clinicians that some biochemical tests are more prone to interference from unusual serum constituents than others-and that quality assurance schemes can do little about this. An important example of this is tests carried out by immunoassays based on the recognition of molecules by antibodies. The antibodies are largely derived from animal sources and are typically used for measuring hormones, tumour markers, cardiac troponins, and therapeutic drugs and for viral serology.
机译:临床化学分析方法的成功带来了对实验室结果价值的安全感。通过外部保证计划评估的实验室性能质量可以证明这是合理的。尽管如此,在临床医生中还没有广泛认识到某些生化测试比其他血清更容易受到异常血清成分的干扰,并且质量保证计划对此无能为力。一个重要的例子是基于抗体对分子识别的免疫测定法。该抗体主要来源于动物,通常用于测量激素,肿瘤标志物,心肌肌钙蛋白和治疗药物以及病毒血清学。

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