Role of intracellular calcium in fast and slow desensitization of P_2-receptors in PC12 cells

摘要

These results suggest a role for [Ca~2+]_ⅰ in slow rather than fast desensitization of P_2-receptors, thus proposing this divalent cation as an intracellular factor able to provide an efficient and reversible control over receptor activity induced by ATP.