Attenuation of morphine withdrawal symptoms by subtype- selective metabotropic glutamate receptor antagonists

Marian E.Fundytus; Jennifer Ritchie; Terence J.Coderre

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Attenuation of morphine withdrawal symptoms by subtype- selective metabotropic glutamate receptor antagonists

机译：亚型选择性代谢型谷氨酸受体拮抗剂减轻吗啡戒断症状

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摘要

Our results suggest that the development of opioid dependence is affected by mGluR-mediated PI hydrolysis and mGluR-regulated cyclic AMP production.

机译：我们的结果表明，阿片样物质依赖性的发展受mGluR介导的PI水解和mGluR调节的环AMP产生的影响。

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来源
《British Journal of Pharmacology》 |1997年第6期|p.1015-1020|共6页
作者
Marian E.Fundytus; Jennifer Ritchie; Terence J.Coderre;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Opioid; morphine; metabotropic glutamate receptor;

机译：阿片类药物;吗啡;代谢型谷氨酸受体;
入库时间 2022-08-18 00:42:51

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1. Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]. [J] . Satow A, Maehara S, Ise S, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2008,第2期

机译：代谢型谷氨酸受体1拮抗剂与代谢型谷氨酸受体5拮抗剂和代谢型谷氨酸受体2/3激动剂在啮齿类动物中的药理作用：选择性变构代谢型谷氨酸受体1拮抗剂FTIDC的详细研究[4- [1-（ [2-氟吡啶-3-基）-5-甲基-1H-1,2,3-三唑-4-基] -N-异丙基-N-甲基-3,6-二氢吡啶-1（2H）-羧酰胺]。
2. Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine. [J] . Salt TE, Turner JP Neuroscience: An International Journal under the Editorial Direction of IBRO . 1998,第3期

机译：新型代谢型谷氨酸受体-1选择性拮抗剂S-2-甲基-4-羧基苯基甘氨酸减少丘脑的感觉和代谢型谷氨酸受体反应。
3. The selective iGluR1-4 (AMPA) antagonist LY300168 attenuates morphine-withdrawal-induced activation of locus coeruleus neurons and behavioural signs of morphine withdrawal. [J] . Rasmussen K, Vandergriff J Neuropharmacology . 2003,第1期

机译：选择性iGluR1-4（AMPA）拮抗剂LY300168减弱了吗啡戒断所致的蓝绿色斑纹神经元的激活以及吗啡戒断的行为征象。
4. Manifold learning visualization of Metabotropic Glutamate Receptors [C] . Martha-Ivon Cardenas, Alfredo Vellido, Jesus Giraldo International Conference of the Catalan Association for Artificial Intelligence . 2014

机译：代谢谷氨酸受体的歧管学习可视化
5. Metabotropic Glutamate Receptors Effects on Feeding [D] . Cano, Jonathan Rene Charles 2015

机译：代谢型谷氨酸受体对饲料的影响
6. Attenuation of morphine withdrawal symptoms by subtype-selective metabotropic glutamate receptor antagonists [O] . Marian E Fundytus, Jennifer Ritchie, Terence J Coderre 1997

机译：亚型选择性代谢型谷氨酸受体拮抗剂减轻吗啡戒断症状
7. Attenuation of morphine withdrawal symptoms by subtype-selective metabotropic glutamate receptor antagonists [O] . Fundytus, Marian E, Ritchie, Jennifer, Coderre, Terence J 1997

机译：亚型选择性代谢型谷氨酸受体拮抗剂减轻吗啡戒断症状

Attenuation of morphine withdrawal symptoms by subtype- selective metabotropic glutamate receptor antagonists

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