首页> 外文期刊>British Journal of Pharmacology >The inhibition of nicotine-evoked relaxation of the guinea-pig isolated basilar artery by some analgesic drugs and progesterone
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The inhibition of nicotine-evoked relaxation of the guinea-pig isolated basilar artery by some analgesic drugs and progesterone

机译:某些止痛药和孕酮对尼古丁引起的豚鼠离体基底动脉舒张的抑制作用

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摘要

1. The purpose of this study was to investigate the mechanism of nicotine-evoked relaxation of the guinea-pig isolated basilar artery and to study the effects of drugs associated with the aetiology or treatment of migraine on the nicotine response. 2. The guinea-pig isolated basilar artery, pre-contracted with prostaglandin F_2α(PGF_2α), IN THE PRESENCE OF ATROPINE (3 μm) and guanethidine (3μM), relaxed on addition of nicotine (0.1 mM) in Approximately 50/100 of preparations.
机译:1.这项研究的目的是研究尼古丁引起的豚鼠离体基底动脉舒张的机制,并研究与病因或偏头痛有关的药物对尼古丁反应的影响。 2.在存在阿托品(3μm)和胍乙啶(3μM)的情况下,先与前列腺素F_2α(PGF_2α)预收缩的豚鼠离体基底动脉在加入约50/100的尼古丁(0.1 mM)后放松准备。

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