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Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats

机译:高血压和正常血压大鼠肠系膜动脉的内皮源性舒张,收缩和超极化因子

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摘要

1. Differences in the acetylcholine (Ach)-induced endothelium-dependent relaxation and hyperpolarization of the mesenteric arteries of Wistar Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP) were studied. 2. Relaxation was impaired in preparations from SHRSP and tendency to reverse the relaxation was observed at high concentrations of Ach in these preparations.
机译:1.研究了乙酰胆碱(Ach)诱导的Wistar Kyoto大鼠(WKY)和易发中风自发性高血压大鼠(SHRSP)的肠系膜动脉内皮依赖性舒张和超极化。 2. SHRSP制剂的松弛作用减弱,并且在高浓度的Ach中观察到扭转松弛趋势。

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