Meta-analysis of age-related gene expression profiles identifies common signatures of aging

João Pedro de Magalhães1*† João Curado2 and George M. Church1

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Meta-analysis of age-related gene expression profiles identifies common signatures of aging

机译：年龄相关基因表达谱的荟萃分析确定了衰老的常见特征

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Motivation: Numerous microarray studies of aging have been conducted, yet given the noisy nature of gene expression changes with age, elucidating the transcriptional features of aging and how these relate to physiological, biochemical and pathological changes remains a critical problem.

机译：动机：已经进行了许多关于衰老的微阵列研究，但是考虑到基因表达随年龄变化的嘈杂性质，阐明衰老的转录特征以及这些转录特征与生理，生化和病理变化之间的关系仍然是一个关键问题。

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《Bioinformatics》 |2009年第7期|p.875-881|共7页
作者
João Pedro de Magalhães1*† João Curado2 and George M. Church1;
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作者单位

1Department of Genetics, Harvard Medical School, Boston, MA 02115, USA and 2Escola Superior de Biotecnologia, 4200 Porto, Portugal;

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收录信息美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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正文语种 eng
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1. Meta-analysis of age-related gene expression profiles identifies common signatures of aging [J] . de Magalhaes Joao Pedro, Curado Joao, Church George M. Bioinformatics . 2009,第7期

机译：年龄相关基因表达谱的荟萃分析确定了衰老的常见特征
2. Cross-platform meta-analysis of multiple gene expression profiles identifies novel expression signatures in acquired anthracycline-resistant breast cancer [J] . Lee Young Seok, Ryu Seung Won, Bae Se Jong, Oncology reports . 2015,第4期

机译：多种基因表达谱的跨平台荟萃分析确定了获得性蒽环类耐药性乳腺癌中的新表达特征
3. A meta-analysis of caloric restriction gene expression profiles to infer common signatures and regulatory mechanisms [J] . Michael Plank, Daniel Wuttke, Sipko van Dam, Molecular BioSystems . 2012,第4期

机译：热量限制基因表达谱的荟萃分析，以推断出共同的特征和调控机制
4. Age-related subpathway detection through meta-analysis of multiple gene expression datasets [C] . Dimitrakopoulos Georgios N., Vrahatis Aristidis G., Balomenos Panos, International Conference on Digital Signal Processing . 2015

机译：通过多基因表达数据集的荟萃分析检测年龄相关的子途径
5. Identification and comparison of gene expression signatures in the nigrostriatal system of Parkinson's disease brains and animal models: Evidence for common pathologic changes. [D] . Miller, Renee Marie. 2005

机译：帕金森氏病大脑和动物模型黑质纹状体系统中基因表达特征的鉴定和比较：常见病理变化的证据。
6. Meta-analysis of age-related gene expression profiles identifies common signatures of aging [O] . João Pedro de Magalhães, João Curado, George M. Church -1

机译：年龄相关基因表达谱的荟萃分析确定了衰老的常见特征
7. Meta-analysis of age-related gene expression profiles identifies common signatures of aging [O] . de Magalhães, João Pedro, Curado, João, Church, George M. 2009

机译：年龄相关基因表达谱的荟萃分析确定了衰老的常见特征

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

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