Importancia de los estudios de biodisponibilidad y de la simulacion matematica en el desarrollo de nuevas formulaciones de liberacion programada

摘要

Computer simulation based on pharma- cokinetic data either from bibliography or from bioavailability studies provides information that makes it an essential tool for innovative laboratories both to formulate different alternatives at the beginning of the design of a new pharma- ceutical dosage form and to follow and asses its development.