Construction of an electrochemical aptasensor based on a carbazole-bearing porous organic polymer for rapid and ultrasensitive detection of penicillin

摘要

A carbazole-bearing porous organic polymer (POP) was successfully prepared by an efficient Friedel - Crafts coupling reaction of 2,4,6-tri(9H-carbazol-9-yl)-1,3,5-triazine and 2,4,6-tris(bromomethyl)mesitylene. The assynthesized POP can load aptamers to fabricate an electrochemical aptasensor because of its high surface area, outstanding stability, and extended pi-conjugation structure, which can rapidly monitor penicillin (PCL) with excellent sensitivity, high selectivity, fine reproducibility, and good stability. More importantly, the POPbased aptasensor can precisely detect trace PCL in various real samples.