A high speed three-dimensional spectral domain optical coherence tomography with <2 μm axial resolution using wide bandwidth femtosecond mode-locked laser

摘要

We have developed an ultra-high-resolution optical coherence tomography (OCT) equipment, using a 200?nm bandwidth spectrometer and a mode-locked femtosecond laser. We have characterized this OCT, obtaining high spatial resolution in the axial direction of less than 2?μm in air via single scanning, within only 20 ms. This corresponds to an ultra-high resolution of less than 1.3?μm for measurements at the fundus retina. High resolution and high speed imaging enables us to selectively obtain a clear three dimensional (3D) lamina cribrosa itself from a 3D optic disc (OD) image in vivo.