Photosensitive biosensor array system using optical addressing without an addressing circuit on array biochips

摘要

This paper introduces a photosensitive biosensor array system with a simple photodiode array thatndetects photocurrent changes caused by reactions between probe and target molecules. Using opticalnaddressing, the addressing circuit on the array chip is removed for low-cost application, and real cellnaddressing is achieved using an externally located computer-controllable light-emitting diode arraynmodule. The fabricated biosensor array chip shows a good dynamic range of 1–100 ng/mL undernprostate-specific antigen detection, with an on-chip resolution of roughly 1 ng/mL. © 2010nAmerican Institute of Physics. u0004doi:10.1063/1.3486179