High-T_c superconducting quantum interference device recordings of spontaneous brain activity: Towards high-T_c magnetoencephalography

摘要

We have performed single- and two-channel high transition temperature (high-T_c) superconducting quantum interference device (SQUID) magnetoencephalography (MEG) recordings of spontaneous brain activity in two healthy human subjects. We demonstrate modulation of two well-known brain rhythms: the occipital alpha rhythm and the mu rhythm found in the motor cortex. We further show that despite higher noise-levels compared to their low-T_c counterparts, high-T_c SQUIDs can be used to detect and record physiologically relevant brain rhythms with comparable signal-to-noise ratios. These results indicate the utility of high-T_c technology in MEG recordings of a broader range of brain activity.