Single and double grating-based X-ray microtomography using synchrotron radiation

摘要

Hard X-ray phase contrast imaging techniques have become most suitable for the non-destructive three-dimensional visualization of soft tissues at the microscopic level. Among the hard X-ray grating interferometry methods, a single-grating approach (XSGI) has been implemented by simplifying the established double-grating interferometer (XDGI). We quantitatively compare the XSGI and XDGI tomograms of a human nerve and demonstrate that both techniques provide sufficient contrast to allow for the distinction of tissue types. The two-fold binned data show spatial resolution of (5.2 ± 0.6) μm and (10.7 ± 0.6) μm, respectively, underlying the performance of XSGI in soft tissue imaging.