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Magnetic microscopic imaging with an optically pumped magnetometer and flux guides

机译:带有光学泵浦磁力计和磁通量导管的磁镜成像

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摘要

By combining an optically pumped magnetometer (OPM) with flux guides (FGs) and by installing a sample platform on automated translation stages, we have implemented an ultra-sensitive FG-OPM scanning magnetic imaging system that is capable of detecting magnetic fields of ~20 pT with spatial resolution better than 300 μm (expected to reach ~10 pT sensitivity and ~100μm spatial resolution with optimized FGs). As a demonstration of one possible application of the FG-0PM device, we conducted magnetic imaging of micron-size magnetic particles. Magnetic imaging of such particles, including nano-particles and clusters, is very important for many fields, especially for medical cancer diagnostics and biophysics applications. For rapid, precise magnetic imaging, we constructed an automatic scanning system, which holds and moves a target sample containing magnetic particles at a given stand-off distance from the FG tips. We show that the device was able to produce clear microscopic magnetic images of 10μn-size magnetic particles. In addition, we also numerically investigated how the magnetic flux from a target sample at a given stand-off distance is transmitted to the OPM vapor cell.
机译:通过将光泵磁力计(OPM)与磁通量导管(FG)结合在一起并在自动平移台上安装样品平台,我们实现了一种超灵敏的FG-OPM扫描磁成像系统,该系统能够检测约20个磁场pT的空间分辨率优于300μm(使用优化的FG有望达到〜10 pT的灵敏度和〜100μm的空间分辨率)。为了演示FG-0PM装置的一种可能应用,我们进行了微米级磁性颗粒的磁性成像。此类粒子(包括纳米粒子和团簇)的磁成像在许多领域都非常重要,特别是对于医学癌症诊断和生物物理学应用而言。为了实现快速,精确的磁成像,我们构建了一个自动扫描系统,该系统可以在距FG尖端一定的固定距离处保持并移动包含磁性颗粒的目标样品。我们证明该设备能够产生10μn大小的磁性颗粒的清晰的微观磁性图像。此外,我们还通过数值研究了在给定间隔距离下来自目标样品的磁通量如何传输到OPM蒸气室。

著录项

  • 来源
    《Applied Physics Letters》 |2017年第4期|043702.1-043702.5|共5页
  • 作者单位

    P-21, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA;

    P-21, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA;

    P-21, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA,Department of Chemical Engineering, National Tsing Hua Jniversity, 101, Sec. 2, Kuang-Fu Rd., Hsinchu 30013, Taiwan;

    P-21, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
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