首页> 外文期刊>The Annals of Occupational Hygiene >Biological Monitoring the Exposure to Polycyclic Aromatic Hydrocarbons of Coke Oven Workers in Relation to Smoking and Genetic Polymorphisms for GSTM1 and GSTT1
【24h】

Biological Monitoring the Exposure to Polycyclic Aromatic Hydrocarbons of Coke Oven Workers in Relation to Smoking and Genetic Polymorphisms for GSTM1 and GSTT1

机译:生物监测焦炉工人多环芳烃暴露与GSTM1和GSTT1的吸烟和遗传多态性的关系

获取原文
获取原文并翻译 | 示例
       

摘要

Occupational exposure to polycyclic aromatic aromatic hydrocarbons(PAH) increases the risk of developing lung cancer. Human exposure is often demonstrated by increased internal levels of PAH metabolites and of markers for early biological effects, like DNA adducts and cytogenetic aberrations. Objective: This study aimed to assess whether the current exposure to PAH of coke oven workers In a Dutch plant induced biological effects, and to determine if these effects are influenced by tobacco Smoking and by genetic polymorphisms for the glutathione S-transferase genes GSTM1 and GSTT1.
机译:职业暴露于多环芳族芳香烃(PAH)会增加患肺癌的风险。人体暴露通常通过PAH代谢物的内部水平升高和早期生物学效应的标志物(如DNA加合物和细胞遗传学畸变)来证明。目的:本研究旨在评估荷兰工厂中焦炉工人当前暴露于多环芳烃是否引起生物效应,并确定这些效应是否受到吸烟和谷胱甘肽S-转移酶基因GSTM1和GSTT1遗传多态性的影响。 。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号