Could Pesticide Toxicology Studies be More Relevant to Occupational Risk Assessment?

摘要

Pesticide toxicology study design has evolved from concern for oral exposure via food resi- dues. The emphasis on the oral route does not generally apply to workers that are exposed primarily via the dermal route either handling pesticides or re-entering treated fields. As a result numerous assumptions about how oral toxicology results relate to dermal exposure must be made when conducting worker risk assessments. These assumptions introduce a high degree of uncertainty.