首页> 外文期刊>American journal of respiratory and critical care medicine >Impairment of neural nitric oxide-mediated relaxation after antigen exposure in guinea pig airways in vitro
【24h】

Impairment of neural nitric oxide-mediated relaxation after antigen exposure in guinea pig airways in vitro

机译:豚鼠气管内抗原暴露后神经一氧化氮介导的舒张功能受损

获取原文
获取原文并翻译 | 示例
       

摘要

Nitric oxide (NO), a neurotransmitter of inhibitory nonadrenergic noncholinergic (iNANC) nerves in airways, is a radical with a short half-life, and its function may be modified by airway inflammation. To test this hypothesis, we examined whether airway allergic inflammation affects iNANC responses Mediated by NO in guinea pigs in vitro. Animals sensitized with ovalbumin (OA) were challenged With 0.03/100 OA (OA group) or saline (saline group) by inhalation on 3 consecutive days.
机译:一氧化氮(NO)是气道中抑制非肾上腺能非胆碱能(iNANC)神经的神经递质,是一种半衰期短的自由基,其功能可能会因气道炎症而改变。为了检验该假设,我们检查了气道过敏性炎症是否影响豚鼠体外NO介导的iNANC反应。连续3天通过吸入0.03 / 100 OA(OA组)或生理盐水(盐水组)攻击被卵清蛋白(OA)致敏的动物。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号