Increased vascularity of the bronchial mucosa in mild asthma

摘要

Airway-wall remodeling leading to thickening of the bronchial wall in asthma has been invoked to ac- count for airflow obstruction and increased bronchial reactivity to provocative stimuli. Bronchial-wall changes characteristic of asthma are thought to include increased vascularity with vasodilatation. The contention that inflammatory mediators cause bronchial vasodilatation and that growth factors May induce increased vascularity is based on little structural evidence.