Sensitization to aspergillus fumigatus and lung function in children with cystic fibrosis

摘要

Colonization with Aspergillus fumigatus (Af) constitutes a common finding in children with cystic fibrosis (CF). The relationship between sensitization to Af and lung function (LF) was studied in 118 patients with CF (61 girls and 57 boys; mean age: 14.3yr; SD: 7yr). Mean follow up was 2.2 yr. On av- reage, 8.1 (SD:4.8) LF tests were performed per patient. Measurement of total lgE and specific lgE antibodies to Af, and a skin prick test (SPT) for Af, were done once a year.