Transfection microarray for genome-wide gene validation

摘要

Cell Informatics Research Group of Research Institute for Cell Engineering has developed a novel DNA microarray for multiple gene transfection. We found a method to significantly increase the on-chip transfection efficiency. Real-time and multiple gene transfection assays are performed on the microarrays under the variable tissue culture conditions. The newly developed microarrays are applied to analyze intracellular signaling pathways.