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The Importance of Brain Infarct Size and Location in Predicting Outcome after Stroke

机译:脑梗塞大小和位置在预测中风后结局中的重要性

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Fifty-six consecutive elderly ( ≥ 65 years) patients, admitted for acute stroke to a geriatric department were included in the study and underwent CT scanning. Functional status was graded according to the modified Rankin scale. Three patients had primary intra-cerebral haemorrhage, 22 deep hemispheric infarct, 17 had anterior circulation cortical infarcts, five had posterior circulation infarcts and in nine the CT scan was normal. Stroke risk factors were equally distributed among the different CT scan groups, and all three larger groups had similar rates of non-neurological major complications including death (41%). However, independence in ADL (Rankin 0-2) was observed in 72% of deep infarct survivors, but only 15% of the cortical infarct group (p = 0.0018). For the normal scan group, functional recovery was intermediate. In the cortical infarct group, patients with an infarct of ≥ 50 mm mean diameter (five cases) showed worse functional recovery than did eight patients with small infarcts. The mean difference between pre- and post-stroke Rankin score (DR) was 3.4 for the larger infarct patients and 1.9 for the smaller infarct group (p = 0.027). Pearson correlation revealed a direct relationship between the infarction size and DR (p = 0.039). Such a relationship was not observed For the deep hemispheric group.
机译:该研究纳入了56名连续老年患者(≥65岁),因老年卒中而进入老年科,并接受了CT扫描。根据改良的兰金量表对功能状态进行分级。原发性脑内出血3例,深半球梗死22例,前循环皮质梗死17例,后循环梗塞5例,CT扫描9例正常。脑卒中危险因素平均分布在不同的CT扫描组中,并且所有三个较大的组具有相似的非神经系统主要并发症发生率,包括死亡率(41%)。但是,在72%的深层梗死幸存者中观察到ADL的独立性(Rankin 0-2),而在皮质梗死组中只有15%(p = 0.0018)。对于正常的扫描组,功能恢复是中等的。在皮层梗死组中,平均直径≥50 mm的梗塞患者(5例)的功能恢复较8例小梗塞患者差。较大梗死患者的卒中前后兰金评分(DR)的平均差为3.4,较小梗死组为1.9(p = 0.027)。皮尔逊相关性显示梗死面积与DR之间存在直接关系(p = 0.039)。对于深半球组没有观察到这种关系。

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