Three-Dimensional Assembly of Polymer Microstructures at Low Temperatures

摘要

Polymer-based biomedical microdevices containing environmentally sensitive biomolecules are attracting increased interest. A critical requirement is the ability to assemble these devices at low temperatures in order to minimize denaturing. For instance, micro-arrays and microfluidic biochips need to be sealed with a lid, and the construction of three-dimensional tissue engineering scaffolds requires bonding of multiple two-dimensional layers with micro-anosized patterns.