Structurally Controlled Bio-hybrid Materials Based on Unidirectional Association of Anisotropic Microparticles with Human Endothelial Cells

摘要

In recent decades, biomedical researchers have increasingly realized the importance of local interactions between synthetic materials and cells for their macroscopic functionality. The groundbreaking progress in the biological sciences has led to a push towards custom-tailored biomaterials with precisely designed physico-chemical properties at the nano- and microscale.To date, a range of different approaches towards custom-tailored biomaterials exist based on different types of materials, such as hydrogels,microfabricated biomaterials,or electrospun fiber scaffolds.