Protein-Size Molecularly Imprinted Polymer Nanogels as Synthetic Antibodies, by Localized Polymerization with Multi-initiators

摘要

We report the synthesis of soluble molecularly imprinted polymer nanogels as synthetic antibodies, with dimensions and molecular weights dose to those of biological antibodies. Antibodies are invaluable tools in areas such as medicine, medical diagnostics, and analytical chemistry, since they are able to bind their antigen with a high affinity and selectivity.