On/Off-Switchable Zipper-Like Bioelectromcs on a Graphene Interface

摘要

Smart and flexible bioelectronics on graphene have emerged as a new frontier in the field of biosensors. Graphene has begun to be seen as an ideal signal transducer and a promising alternative for the production of low-cost bioelectronic devices. However, biological systems used in these devices suffer from a lack of control and regulation. There is an obvious need to develop "switchable" and "smart" interfaces for both fundamental and applied studies. Here, we report for the first time the fabrication of an on/off-switchable zipper-like graphene interface, which is used to manipulate biomolecular interactions. Using electrochemical measurements, we demonstrate that interfacial bio-electrochemical properties can be tuned by modest changes in temperature. Such an ability to independently regulate the behaviour of the interface has important implications for the design of novel bioreactors, biofuel cells and biosensors with inbuilt self-control features.