Enhancing Quantum Dots for Bioimaging using Advanced Surface Chemistryn and Advanced Optical Microscopy: Application to Silicon Quantum Dotsn (SiQDs)

摘要

Fluorescence lifetime imaging microscopy is successfully demonstrated in both one-and two-photon cases with surface modified, nanocrystalline silicon quantum dots in the context of bioimaging. The technique is further demonstrated in combination with Forster resonance energy transfer studies where the color of the nanoparticles is tuned by using organic dye acceptors directly conjugated onto the nanoparticle surface.