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首页> 外文期刊>Advanced Materials >Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy
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Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy

机译：金纳米棒，DNA折纸和多孔硅纳米粒子功能化的生物相容性双重乳液，可用于多种靶向治疗和抗体联合治疗。

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摘要

Gold nanorods, DNA origami, and porous silicon nanoparticle-functionalized biocompatible double emulsion are developed for versatile molecular targeted therapeutics and antibody combination therapy. This advanced photothermal responsive all-in-one biocompatible platform can be easily formed with great therapeutics loading capacity for different cancer treatments with synergism and multidrug resistance inhibition, which has great potential in advancing biomedical applications.
机译：金纳米棒，DNA折纸和多孔硅纳米粒子功能化的生物相容性双乳胶被开发用于多种分子靶向治疗和抗体联合治疗。这种先进的光热响应多合一生物相容性平台可轻松形成，具有强大的治疗负荷能力，可通过协同作用和多种药物耐药性抑制作用，用于不同的癌症治疗，这在推进生物医学应用方面具有巨大潜力。

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  • 来源
    《Advanced Materials》 |2016年第46期|10195-10203|共9页
  • 作者

    Kong Feng; Zhang Hongbo; Qu Xiangmeng; Zhang Xu; Chen Dong; Ding Ruihua; Makila Ermei; Salonen Jarno; Santos Helder A.; Hai Mingtan;

  • 作者单位

    Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing Key Lab Funct Mat Mol & Struct Construct, Beijing 100083, Peoples R China|GRIKIN Adv Mat Co Ltd, 33 Chaoqian Rd, Beijing 102200, Peoples R China;

    Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing Key Lab Funct Mat Mol & Struct Construct, Beijing 100083, Peoples R China|Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA|Univ Helsinki, Fac Pharm, Div Pharmaceut Chem & Technol, FI-00014 Helsinki, Finland;

    Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing Key Lab Funct Mat Mol & Struct Construct, Beijing 100083, Peoples R China|Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA|East China Normal Univ, Sch Chem & Mol Engn, 500 Dongchuan Rd, Shanghai 200241, Peoples R China;

    Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA|Cape Breton Univ, 1250 Grand Lake Rd, Sydney, NS B1P 6L2, Canada;

    Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA;

    Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA;

    Univ Turku, Dept Phys, Lab Ind Phys, FI-20014 Turku, Finland;

    Univ Turku, Dept Phys, Lab Ind Phys, FI-20014 Turku, Finland;

    Univ Helsinki, Fac Pharm, Div Pharmaceut Chem & Technol, FI-00014 Helsinki, Finland;

    Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing Key Lab Funct Mat Mol & Struct Construct, Beijing 100083, Peoples R China|Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA;

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