Effect of genistein and quercetin on proliferation, collagen synthesis, and type Ⅰprocollagen mRNA levels of rat hepatic stellate cells

摘要

GC(25-70 μmol/ L)and QU(6.25-50μmol/L)concentration- Dependently reduced serum-driven HSC-T6 celle prolifera- Tion and collagen synthesis associated with a suppression Of type Ⅰ procollagen mRNA level. GE and QU inhibited hepatic stellate cell proliferation and Collagen synthesis that might have a protective role Against liver fibrosis.