Expression of androgen receptor in the developing rat Epididymis and its regulation by androgens

摘要

Objective To study the distribution, developmental patterns, and hormonal control of androgen re- ceptiors (AR) in the developing and ethane dimethane sulfonate (EDS) treated male SD rat epididymis. Methods The ABC technique of immunohistochemistry and image analysis were used to assess optodensity means (OPTDM) of AR, Providing a measure of relative nuclear AR concentration. Results The specific AR immunostaining was observed in The nuclei of epididymal epithelium, peritubular smooth muscle cells and intertubular connective tissue cells.