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Links between looking and speaking in autism and first-degree relatives: insights into the expression of genetic liability to autism

机译:自闭症和一级亲属的看与说之间的联系:对自闭症遗传责任表达的见解

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摘要

BackgroundRapid automatized naming (RAN; naming of familiar items presented in an array) is a task that taps fundamental neurocognitive processes that are affected in a number of complex psychiatric conditions. Deficits in RAN have been repeatedly observed in autism spectrum disorder (ASD), and also among first-degree relatives, suggesting that RAN may tap features that index genetic liability to ASD. This study used eye tracking to examine neurocognitive mechanisms related to RAN performance in ASD and first-degree relatives, and investigated links to broader language and clinical-behavioral features.
机译:背景快速的自动命名(RAN;以阵列形式显示的熟悉项目的命名)是一项任务,该任务利用了在许多复杂的精神病学状况中受到影响的基本神经认知过程。在自闭症谱系障碍(ASD)中以及一级亲属中已经多次观察到RAN的缺陷,这表明RAN可能利用了索引遗传性疾病对ASD的特征。这项研究使用眼动追踪来检查与ASD和一级亲属中RAN性能相关的神经认知机制,并调查与更广泛的语言和临床行为特征的联系。

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